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However, this intra-individual variation is relatively stable over time which is a phenomenon likely due to variation in genes regulating glutathione levels in RBCs [32]

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doi: 10.1152/ajpendo.00441.2001

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Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity

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On the other hand 60 mutations or their combinations were documented, all of precise nature taking into account that the total deficiency is incompatible with life 23

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